Objective To discuss the effects of using all‑round protective mask (positive pressure) or disposable hood (non‑positive pressure) on tracheal intubation in patients with severe COVID‑19. Methods Twenty COVID‑19 patients who underwent endotracheal intubation from February 16 to February 29, 2020 were retrospectively enrolled, including an all‑round protective mask (positive pressure) group with 9 anesthesiologists wearing all‑round protective mask (positive pressure) and a disposable hood (non‑positive pressure) group with 11 anesthesiologists wearing disposable hood (non‑positive pressure). Then, the following data were collected: the time‑consuming of tracheal intubation, anxiety score during tracheal intubation, endotracheal intubation satisfaction, the presence of screen fogging and obvious suffocation. Results Anesthesiologists in the all‑round protective mask (positive pressure) group presented remarkably lower anxiety scores of tracheal intubation than those in the disposable hood (non‑positive pressure) group (P<0.05). There was no significant difference in intubation time‑consuming, satisfaction, screen fogging and obvious feeling of suffocation between the two groups (P>0.05). Conclusions Compared to disposable hood (non‑positive pressure), all‑round protective mask (positive pressure) can relieve the anxiety of anesthesiologists to some extent. Both of them can achieve the same effects on the time‑consuming and satisfaction of endotracheal intubation. Within a short period of time (less than 30 min), no screen fogging and obvious feeling of suffocation appear in the two groups.