国际麻醉学与复苏杂志   2020, Issue (12): 0-0
    
认知储备与围术期认知障碍
焦宏伟, 张卫卫, 吕志敢, 张建文, 高明1()
1.山西医学科学院(山西白求恩医院)
Cognitive reserve and postoperative cognitive dysfunction
 全文:
摘要:

术后认知功能障碍是思维过程的一种微妙障碍 ,至今无有效的治疗和预防手段。减少术后认知不良的发生和促进术后认知功能的恢复是当代麻醉的重点。越来越多的研究认为可以将认知储备作为POCD的预防手段。本文将阐述POCD和认知储备的病理生理机制,结合国外研究,概述其相关性。分析认知储备在治疗和预防POCD方面的有效性,阐述产生作用的机制,为临床治疗和预防POCD提供参考。

关键词: POCD 认知储备 病理生理机制
Abstract:

Postoperative cognitive dysfunction is a kind of obstacle in the thinking process, so far there is no effective treatment and prevention means.More and more attention has been paid to reduce the occurrence of postoperative cognitive impairment and promote the recovery of postoperative cognitive function and some studies have found that cognitive reserve can be used as a preventive measure for POCD.We reviewed foreign literature to elucidate the pathophysiological mechanisms of POCD and cognitive reserve and to summarize their correlation. The effectiveness and mechanism of cognitive reserve in the treatment of POCD were analyzed to provide reference for the clinical treatment and prevention of POCD.

Key words: Postoperative cognitive dysfunction Cognitive reserve Pathophysiological mechanism