阻塞型睡眠呼吸暂停综合征（obstructive sleep apnea syndrome, OSAS）是临床常见的睡眠障碍性疾病，其导致的代谢紊乱及全身各系统的损伤已经得到越来越多的研究和证实。自主神经系统（autonomic nervous system, ANS）与睡眠关系密切，许多睡眠障碍的患者会出现ANS损害的症状。文章综述了ANS功能失调在OSAS中的作用，主要包括ANS功能失调引起的心血管和非心血管系统病理生理改变，希望能为临床上OSAS相关疾病的防治及围手术期的麻醉管理提供理论依据。
Obstructive sleep apnea syndrome (OSAS) is a common clinical sleep disorder, which leads to metabolic disorders and damage to various systems of the body has been more and more research and confirmed. There is a close relationship between autonomic nervous system (ANS) and sleep. Studies have found that many patients with sleep disorders will have symptoms of autonomic nerve damage.This article reviews the role of ANS dysfunction in OSAS, including pathophysiological changes in the cardiovascular and non‑cardiovascular systems caused by ANS dysfunction. It is hoped that it can provide a theoretical basis for the clinical prevention and treatment of OSAS‑related diseases and perioperative anesthesia management.
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