国际麻醉学与复苏杂志   2021, Issue (8): 20-20
    
脑深部电刺激手术麻醉管理进展
郑思豪, 蔡晓东, 刘志恒1()
1.深圳市第二人民医院/深圳大学第一附属医院麻醉科、脑科中心
Research advances on anesthesia management of deep brain stimulation surgery
 全文:
摘要:

脑深部电刺激(deep brain stimulation, DBS)手术作为神经退行性疾病的主要治疗手段,具有创伤小、可逆、安全性高、长期疗效显著的优点。DBS手术的麻醉方法包括局部麻醉、清醒镇静、监护下麻醉管理(monitored anesthesia care, MAC)、睡眠‑清醒‑睡眠(asleep‑awake‑asleep, AAA)麻醉和全身麻醉,目前关于该手术麻醉管理的研究较少。文章就DBS手术的麻醉管理进展进行综述,介绍DBS手术的适应证、实施过程,总结麻醉方法、麻醉用药、围手术期管理、并发症防治。DBS手术麻醉方法和麻醉用药的选择目前仍处于探索阶段,未来还需要更多高质量的研究进一步指导DBS手术的麻醉管理。

关键词: 脑深部电刺激手术; 神经退行性疾病; 麻醉; 围手术期; 并发症
Abstract:

Deep brain stimulation (DBS) surgery, as the main treatment for neurodegenerative diseases, has the advantages of little invasion, reversibility, high safety, and significant long‑term efficacy. Anesthesia methods for deep brain stimulation surgery include local anesthesia, conscious sedation, monitored anesthesia care (MAC), asleep‑awake‑asleep (AAA) anesthesia, and general anesthesia. At present, there are few review on the anesthesia management of this surgery. In this paper, by introducing the indications and process of DBS surgery and summarizing anesthesia methods, anesthetic agents, perioperative management, and prevention and treatment of complications, the advances of anesthesia management in DBS surgery is expounded. The choice of anesthesia methods and drugs for DBS surgery is still in the exploratory stage. More high‑quality research results are needed to guide the anesthesia management of DBS surgery.

Key words: Deep brain stimulation surgery; Neurodegenerative diseases; Anesthesia methods; Anesthetic agents; Perioperative management; Complications