Cardiac patients undergoing non‑cardiac surgery have a higher risk of anesthesia and surgical complications and mortality than non‑cardiac patients. Preoperative evaluation and preparation are of great importance to improve the safety of anesthesia surgery and speed up patient recovery after surgery. In the current article, the patient presented coronary heart disease (three‑vessel disease), arrhythmia, frequent ventricular premature beats, severe mitral regurgitation, old cerebral infarction, and hypokalemia before surgery. During the surgery, the perfusion of vital organs was maintained, and electrolyte correction, anti‑arrhythmia, anti‑inflammation and anti‑stress treatment, heat preservation and anti‑nausea and vomiting were performed. The patient smoothly completed the surgery and was cured and discharged.