Objective To compare the consistency of ConView anesthesia depth monitoring and Narcotrend anesthesia depth monitoring in target controlled infusion (TCI) of etomidate. Methods A total of 120 patients, aged 18 to 65 years, American Society of Anesthesiologists (ASA) grade Ⅰ or Ⅱ, who were scheduled for middle ear surgery were included. Each patient was subjected to both ConView anesthesia depth monitoring (Ai index) and Narcotrend anesthesia depth monitoring (Nt index). Etomidate was used in combination with remifentanil for TCI anesthesia. The Nt index and Ai index were recorded before induction (T1), 1 min after induction (T2), 3 min after induction (T3), 3 min after intubation (T4), 5 min after intubation (T5), at the beginning of operation (T6), half an hour after operation (T7), 1 h after operation (T8), 1.5 h after operation (T9), at the end of operation (T10), during extubation (T11) and 5 min after extubation (T12). Bland‑Altman consistency analysis was performed to analyze the changes in the two indexes. Results According to Bland‑Altman consistency analysis, the average difference between the overall Nt index and Ai index was 1.20, and the proportion outside the consistency range was 4.58% (66/1 440). The average difference between Nt index and Ai index was larger at T2 (−9.34), and the proportion outside the consistency range was 5.00% (6/120). Conclusion Both domestic ConView anesthesia depth monitoring and Narcotrend monitoring can objectively reflect the real‑time depth of anesthesia in patients undergoing TCI with etomidate.