急性肾损伤（acute kidney injury, AKI）是心脏外科手术常见并发症之一，与围手术期病死率显著相关。目前AKI的发病机制尚未明确，探索新的预测指标有助于早期识别高危患者，并采取有效干预措施预防AKI的发生。一些研究表明尿氧分压（urinary oxygen partial pressure, PuO2）可作为预测AKI的指标。文章对心脏手术相关性急性肾损伤（cardiac surgery‑associated acute kidney injury, CSA‑AKI）的研究进展和PuO2在CSA‑AKI的诊断及其预后预测价值的相关研究进行综述，以期为临床上CSA‑AKI的预测提供新的思路。
Acute kidney injury (AKI) is one of the common complications of cardiac surgery, which is significantly related to perioperative mortality. At present, the pathogenesis of AKI is not yet clear. Exploring new predictive indicators can help identify high‑risk patients in the early stage and take effective intervention measures to prevent the occurrence of AKI. Some studies have shown that urinary oxygen partial pressure (PuO2) can be used as an indicator for predicting AKI. This review summarizes the research advances of cardiac surgery‑associated acute kidney injury (CSA‑AKI) and the diagnostic and prognostic value of PuO2 in CSA‑AKI to provide new ideas for the prediction of CSA‑AKI in clinical practice.
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